The Best IGF-1 Supplements 2022

Older muscular man with surfboard


, which are in a similar category to HGH supplements, work by increasing the production of insulin-like growth factor in the body. IGF-1 is similar in structure to insulin, hence the name insulin-like growth factor.

Part of a group of peptides known as somatomedins, IGF-1 is an endocrine hormone that’s mainly produced by the liver and regulates much of the growth-promoting effects of HGH. In simple terms, human growth hormone (HGH) signals the liver to produce IGF-1, which stimulates cell growth, healing, and development throughout the body.

So when IGF-1 levels increase, it’s a sure indicator that HGH levels are increasing as well – and it’s through IGF-1 that HGH delivers many of its benefits.

Normally, IGF-1 production reaches it’s peak during adolescent and pubescence, rapidly decreasing during adulthood. Significant benefits, however, can be achieved by adults who increase IGF-1 levels by using over-the-counter IGF-1 supplements.

IGF-1 supplements encourage the body to increase it’s own production of IGF-1 which can lead to heightened cell growth and development, healing, strengthening of the tissues, and a wide variety of other “anti-aging” benefits, including:

  • An increase in lean muscle mass
  • Faster metabolism and fat burning
  • Strength and endurance gains
  • A stronger immune system
  • Speedier recovery and healing time
  • An increased sex drive
  • Better cognitive function

The Top 3 Best IGF-1 Supplements of 2023

The following list of recommended IGF-1 supplements was compiled based on our own research as well as personal experience from testing dozens of products. User reviews and feedback were also considered.

Currently, our top-rated picks for the best IGF-1 supplements of 2023 are:


Pituitary Growth Hormone bottle on white background
  • Enhanced physical conditioning.
  • Increased lean muscle mass.
  • Promotes fat loss.
  • Improved recovery and joint protection.
  • Greater strength and stamina.

More Details  Buy Now

GenF20 Plus

GenF20 Plus
  • Anti-aging benefits.
  • Increased physical stamina.
  • Weight loss with decreased body fat.
  • Lean muscle growth.
  • Speeds up metabolic rate.

More Details  Buy Now


Sytropin spray bottle
  • Increases lean muscle mass.
  • Decreases body fat.
  • Improves recovery time.
  • Boosts energy and performance.
  • Enhances the immune system.

More Details  Buy Now

Product Details


PGH-1000 from Anabolic Research is our top-recommended IGF-1 supplement, and it’s by far the best we have researched and tested to date. Formulated to trigger lean muscle growth, increased strength and stamina, weight loss, and improved cognitive function, Pituitary Growth Hormone is the ultimate in hormone optimization.

PGH-1000 was designed to naturally stimulate anabolic activity and metabolic enhancement,  and it’s a highly-effective general performance supplement for promoting lean muscle mass and athletic performance. This product stimulates the metabolism in a way that promotes lean tissue growth with minimal body fat gain, while improving many other aspects of fitness, including deeper sleep, faster healing and recovery, and elevated mood.

PGH-1000 is one of the most efficient and potent products I’ve personally tested, and most other supplements don’t even come close. If you’re looking for massive gains in athletic performance and physical fitness, look no farther than PGH-1000.

WARNING: If you are a professional athlete or otherwise subject to testing by the IOC or other sports governing body, this product may cause you to test positive for performance enhancing drugs.

See Also: My Full PGH-1000 Review


Pituitary Growth Hormone Benefits:

    • The Best IGF-1 Supplements 2022 Stimulates muscle growth.
    • The Best IGF-1 Supplements 2022 Promotes fat loss.
    • The Best IGF-1 Supplements 2022 Improves brain function.
    • The Best IGF-1 Supplements 2022 Greater strength and stamina.
    • The Best IGF-1 Supplements 2022 Accelerates healing and recovery.


GenF20 Plus

GenF20 Plus is another high-quality product manufactured by Leading Edge Health. Like HyperGH 14x, GenF20 Plus takes advantage of a two-pronged approach to raising growth hormone levels by combining a power-packed pill with a highly efficient oral spray, using the best of both worlds to safely and effectively increase IGF-1 production.

GenF20 Plus contains an exact formula herbal extracts, amino acids, and other growth factors that research has shown to increase IGF-1 levels and produce effects such as:

  • Muscle gain
  • Stronger bones
  • Increased energy and motivation
  • A more youthful appearance

…and many other benefits. In fact, after conducting a 12 week double-blind study, researchers noted that GenF20 Plus increased IGF-1 levels by 28% after just 12 weeks. (1)

I’ve used GenF20 Plus and know first-hand what an amazing, proven IGF-1 supplement system it is. With continued use, it can make you look and feel 10, 15, even 20 years younger. Highly recommended.

See Also: My Full GenF20 Plus Review

GenF20 Plus Benefits:

    • The Best IGF-1 Supplements 2022 Increases lean muscle mass.
    • The Best IGF-1 Supplements 2022 Promotes fat loss.
    • The Best IGF-1 Supplements 2022 Boosts energy and stamina.
    • The Best IGF-1 Supplements 2022 Diminishes wrinkles & age-related blemishes.
    • The Best IGF-1 Supplements 2022 Improves memory and focus.
    • The Best IGF-1 Supplements 2022 Increases sex drive.



Sytropin is a potent oral spray supplement made by Speedwinds Nutrition. Using a blend of homeopathic growth hormone and effective IGF-1-releasing herbal extracts and amino acids, Sytropin is a top performer when it comes to IGF-1 supplementation.

Sytropin spray is absorbed into the bloodstream through the mouth’s lining, which is the best way to ensure potency and effectiveness. This way it bypasses the the stomach without being broken down too quickly through the digestive system.

Sytropin is not only a powerful HGH supplement, it’s also a convenient spray that’s fast-acting and gets absorbed into the blood stream quickly for rapid results. Highly recommended.

See Also: My Full Sytropin Review


Sytropin Benefits:

    • The Best IGF-1 Supplements 2022 Promotes lean muscle growth.
    • The Best IGF-1 Supplements 2022 Decreases body fat.
    • The Best IGF-1 Supplements 2022 Speeds up post-workout recovery.
    • The Best IGF-1 Supplements 2022 Boosts energy and performance.
    • The Best IGF-1 Supplements 2022 Strengthens the immune system.


Common Ingredients Used in IGF-1 Supplements

The ingredients found in IGF-1 supplements are often similar to those found in HGH products, and in fact, most HGH supplements work by raising IGF-1 levels. Some of these ingredients include things like:

  • Amino acids
  • Colostrum
  • Deer Antler Velvet
  • GABA

Not surprisingly, these types of supplements are a popular choice among bodybuilders, professional athletes, and people looking for anti-aging benefits.

L-Ornithine and L-Arginine

L-arginine is a semi-essential amino acid and has a number of important functions. Two of these functions include stimulating the secretion growth hormone IGF-1.

L-ornithine has also been proven to increase the production of HGH. L-ornithine is an amino acid that can increase blood flow, muscle performance, and muscle growth.

Studies have shown that L-arginine combined with L-ornithine increases HGH and IGF-1 levels.

One 3-week study involved athletes who were randomly given either a combination of L-ornithine and L-arginine, or a placebo. Researchers observed that the athletes who were given L-ornithine and L-arginine saw significant increases in both growth hormone IGF-1 serum levels. (2)

The study showed that when taking l-arginine with l-ornithine you can expect to see an increase in HGH and IGF-1 after intense resistance training.


Colostrum, which is a fluid found in the breast milk of mammals (including humans) during late pregnancy or the days following birth. Colostrum promotes the production of human growth hormone.

Colostrum contains insulin-like growth factors, which are technically by-products of HGH. In fact,  IGF-1 levels are measured  to evaluate the amount of HGH produced in the body.

Bovine colostrum is nearly identical to human colostrum. However, bovine colostrum contains more growth factors (i.e. growth-stimulating hormones) than human colostrum.

IGF-1 is believed to be responsible for the health-enhancing effects of HGH. Colostrum provides a number of excellent benefits, such as boosted immunity, enhanced healing, increased muscle mass, stronger bones and anti-aging.

Deer Antler Velvet

Another common ingredient used for raising IGF-1 levels is deer antler velvet. Once banned by the World Anti-Doping Agency, deer antler velvet contains several important growth factor components, including IGF-1.

However, because IGF-1 is known to aid in the regeneration of cartilage, tendons, and joints, many athletes continue to use it. In particular, it is used  following strenuous workouts and grueling competitions.

IGF-1 has been shown to accelerate healing and recovery, and a 100% legal way to experience this for yourself is to take a supplement containing deer antler velvet.


According anecdotal reports found on various bodybuilding websites, GABA supplements are claimed to boost the production of HGH. This is certainly true for GABA that’s naturally produced by the body, but evidence also supports the idea that oral GABA supplements can trigger HGH and IGF-1 production as well.

Men participating in a study at Virginia’s Shenandoah University were given either GABA supplements or a placebo prior to engaging in resistance training exercises. Researchers found that GABA increased the total amount of growth hormone the subjects produced as a result of training by a whopping 480 percent! (3)

The researchers concluded that ingested GABA supplements can significantly elevate resting and post-exercise growth hormone levels.

In another study, participants receiving GABA supplementation showed significant improvement in physical fitness, vitality, and mental function. IGF-1 levels within the GABA group also increased compared to the levels before intake. Additionally, there were no adverse effects or clinically concerning changes were observed. (4)

Additional research has also shown that GABA supplementation does indeed increase IGF-1 levels. (5)



3 thoughts on “The Best IGF-1 Supplements 2022”

  1. I’ve been using Pituitary Growth Hormone and it makes a 48 year-old man like me feel like I’m in my 20s again. No BS. I’m on my 2nd purchase and this time I got the 3 for 2 deal. More energy, better mood and motivation, my joint and back pain are pretty much gone. Joints feel smooth and move way better. For sure feel a testosterone boost. Muscles feel bigger and losing weight.


Leave a Comment